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Author6 Posts
  #1

How does injection with epinephrine prolongs the effects of local anesthetics? confused

  #2

By inducing local vasoconstriction and thus prolonging the time by which the local anaethetic is washed away by the blood.



  #3

nodnod

___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #4

The addition of epinephrine to some local anesthetic solutions prolongs duration of action by causing vasoconstriction and decreasing systemic absorption.


___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #5

Would ficks law apply here- say id you decrease flow rate (by vasoconstriction) then you decrease the conc gradient and prolong the rate of diffusion?

  #6

yes epinephrine causes vasoconstriction,which slowz the clearing period of tht local anesthetic...nodnod

___________________
i m not perfect but i wanna get close to it......









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