monam84
Forum Senior
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How does injection with epinephrine prolongs the effects of local anesthetics? 
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| asherif
Forum Newbie
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By inducing local vasoconstriction and thus prolonging the time by which the local anaethetic is washed away by the blood.
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| NNL
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| NNL
Awaitin The Unexpected
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The addition of epinephrine to some local anesthetic solutions prolongs duration of action by causing vasoconstriction and decreasing systemic absorption.
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Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck
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| monam84
Forum Senior
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Would ficks law apply here- say id you decrease flow rate (by vasoconstriction) then you decrease the conc gradient and prolong the rate of diffusion?
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| Ig F
Forum Guru
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yes epinephrine causes vasoconstriction,which slowz the clearing period of tht local anesthetic...
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