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Kaplan Qbank USMLE



Author5 Posts
  #1

Which of the following is a major interleukin produced by CD4+ T helper 1 (TH1) lymphocytes?


A. IL-1

B. IL-2

C. IL-4

D. IL-6

E. IL-8

  #2

IL 4

  #3

IL-2

  #4

The correct answer is B. IL-2 produced by TH1 cells stimulates natural killer (NK) cells and CD8+ T cytotoxic lymphocytes and combines with IL-2 receptors on the TH1 cells to cause "self-stimulation". IL-2 is also involved in downregulating CD4+ T helper 2 lymphocytes.
IL-4 (choice C) is derived from CD4 + T helper 2 cells. It acts to downregulate CD4 + TH1 cells and allows class switching to IgE.

  #5

THANKS will remember it better now







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