avishkar1984
Forum Junior
Topics: 15
Posts: 58
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hi guys
pls help me out with this one:
if a normal person starts consuming salt in excess,then which system will function to bring the balance back to normal?
renin-angiotensin-aldosterone system(it recieves inputs frm macula densa also which measures the sodium delivery)
OR
ADH system(it recieves inputs frm the osmoreceptors in hypothalamus)
i feel the answer shd be adh...
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| indidoc1
Forum Guru
Topics: 50
Posts: 978
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hmm.. according to me, osmolarity is gonna rise.
ADH secretion increases causing free water reabsorption
ANP rescue is gonna come into play (raised salt is a stimulus fr ANP)
i think RAAS in gonna be suppressed bcoz inc salt n water causes inc BP .. read the 3rd factoid in this link http://health.rutgers.edu/factsheets/sodium.htm
so, i think u r right in thinking abt ADH, avishkar
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| jole
Forum Elite
Topics: 6
Posts: 246
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thINK ADH would be a better mechanism
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| verapamil
Forum Newbie
Topics: 2
Posts: 43
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Yup. ADH is responsible for maintaining osmolarity and is stimulated even by a 1% change in sodium conc. (Kaplan physio).
on the other hand, aldosterone is mainly regulated by the pressure in the kidneys via JG cells through the RAAS. in my opinion, macula densa is just an accessory mechanism to help out the JG cells.
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| verapamil
Forum Newbie
Topics: 2
Posts: 43
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let me correct myself.. it's not 1% change in sodium conc. rather 1% change is ECF osmolality. sorry
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| Mikeland
Forum Senior
Topics: 24
Posts: 109
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yes, ADH
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| hanwin
Forum Senior
Topics: 6
Posts: 157
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Yes, definitely ADH.
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| GoodGirl
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