Feyza
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Which of the m.o. below cause highest amount of IgM production upon first exposure ??
S.aureus
Str pneumonia
Nocardia
B.fragilis
Listeria
ALSO GIVE EXP PLZZZ 
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| new_n_lost
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Str pneumonia ??
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| new_n_lost
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Ppl Cmon Ans The Questions Then it becomes useless to Discuss or Post Questions.
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| Feyza
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yup  ıts strep ...but WHHYYYY ??
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O my Lord! Open my chest for me ( grant me self-confidence ) and ease my task for me.Ta-Ha 25-26.
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| new_n_lost
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i really dont know i just made a guess n i was hoping u wud tell m e
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| silver
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Strep. Pneumoniae. Probably because it has a large polysaccharide coat. Polysaccharides are poor immunogens because they rely on response of T-independent B cells. And it's the polysaccharide coat that helps this organism to block complement binding and opsonization.
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| Feyza
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yesss its all about the T independent thing...
in thymus independent antibody response, antigens activate B cells in absence of significant T cell help...that means they dont class switch ( no CD 40 -CD 40 interaction) so IgM is the only immunoglobulin. These antigens are generally large polymers with repeating epitopes such as polisaccarides.Thats why encapsulated organisms cause more than normal amounts of IgM response
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| lq2006
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Str pneumonia
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| SmokyWaters
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yeah I thought the same...T independent activation causes more prolonged prod of IgM ....
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| drduck
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yup....strept pneumo....
i was late....
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| GoodGirl
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I again learned something new.
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| epica
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V. good Q
Thanks Feyza
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