new_n_lost
Politically InCorrect
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A Very Simple Concept Is Being Asked Plz Rethink Ur Answer
A 15-year-old girl complained of anxiety and excessive sweating. She was not taking any medication.
Investigations showed:
TSH concentration 0.9 mU/L (0.5-3.4)
Free T4 concentration 16 pmol/L (10-18)
Total T4 concentration 180 nmol/L (55-145)
Free T3 concentration 8.2 pmol/L (3.5-10.5)
Total T3 concentration 3.3 nmol/L (0.9-2.5).
These results are compatible with which one of the following diagnoses?
1) Factitious thyrotoxicosis
2) Familial dysalbuminemic hyperthyroxinemia
3) Pregnancy
4) Sick euthyroid syndrome
5) Thyrotoxicosis
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| doc179
Forum Guru
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3?
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| mytime
Kick my butt!
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3.
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| treblechar
Forum Junior
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Familial dysalbuminemic hyperthyroxinemia ?
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| new_n_lost
Politically InCorrect
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Ladies U r Right ( treblechar dont know abt u )
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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The symptom complex is intentionally misleading. The patient has a normal TSH and normal free T3 and T4 concentrations, excluding thyrotoxicosis but elevated Total concentrations suggesting a rise in the binding globulins. This can occur in pregnancy.
Sick euthyroidism would be typically associated with low thyroid hormone concentrations.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| silver
Forum Guru
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3. The fact that the total concentrations are raised, indicates there is increase in TBG levels. TBG levels are increased by: pregnancy, estrogen, methadone, heroin, tranquilizers, and clofibrate. When TBG levels are increased eventually a new equilibrium is reached where total conc. are increased, but free hormone conc. and TSH remains normal
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