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Kaplan Qbank USMLE



Author9 Posts
  #1

A 70 year old male was receiving Amiodarone 200 mg daily for intermittent atrial fibrillation. However, he was aware of tiredness and lethargy. He appeared clinically euthyroid with no palpable goiter.

Investigations revealed:

Serum free T4 23pmol/L (9-26)
Serum total T3 0.8 nmol/L (0.9-2.8)
Serum TSH 8.2 mU/L (<5)

Which of the following statements would explain these results?

1) Abnormal thyroxine binding globulin

2) Amiodarone-induced hypothyroidism

3) 'Sick Euthyroid' syndrome

4) Spontaneous hypothyroidism

5) TSH secreting pituitary adenoma

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #2

2

  #3

Anyone Else Guys !!!!!!!!!!!! Ah Cmon ppl show Some Guts

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #4

3) 'Sick Euthyroid' syndrome Cannot be 1) Abnorma thyroxine binding gloobulin total T3 which includes the bound form is less . 2) Amidorone induced .. aint sure 4) Spontaneous Hypothyroid - Cud be ... but T4 are higher 5) NOt a pit secreting Tumour definitely .. or is it raised eyebrow

___________________
... Idle hands are the DeVilS play ground ...

  #5

3-sick euthyroid syndrome

  #6

2) Amiodarone-induced hypothyroidism


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #7

Is it because Amiodorone mimics thyroid hormone so its acts to inhibit TSH?

  #8

amiodarone impairs T4 to T3 conversion

___________________
Every disaster hides an opportunity.

  #9

nod amiodarone induced hypo TH







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