new_n_lost
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A middle-aged patient develops a gelatinous, well-circumscribed mass in her right cerebral hemisphere. Biopsy of the mass reveals neoplastic cells with a "fried egg" morphology.
Which of the following tumors does this patient most likely have?
A. Choroid plexus papilloma
B. Ependymoma
C. Glioblastoma multiforme
D. Oligodendroglioma
E. Pilocytic astrocytoma
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| mytime
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C
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| me007
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http://pathweb.uchc.edu/eAtlas/CNS/1766.htm
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| Addicudo
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D. Oligodendroglioma-- presents with a Fried Egg Apperance on histology !
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| Addicudo
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Oligodendroglioma
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| mytime
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Thanks guys..........instincts are always best ,I suppose.........when u overthink.....eventually always wrong! 
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| ShweHope99.9998
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Thanks, "fried egg shape" .... circle... so ... appear as "OOOOOOOOOOOOO"ligod .
I will try to remember like that .
Do not know about... box shape, may be fried egg in the square shape, cause, fried egg cut on the sides into square, box shape to fit in the square shape sandwich .
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| new_n_lost
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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The correct answer is D.
The tip off for oligodendroglioma is "fried egg" cells, which are tumor cells with round nuclei (the "yolk") and cleared cytoplasm (the "white"). These tumors may contain areas of calcification, hemorrhage, or cysts. They tend to occur in the cerebral hemispheres of middle-aged patients of both sexes, and have a better prognosis (average survival 5 years) than astrocytomas.
The usual tip-off for choroid plexus papilloma (choice A) is a papillary growth in a ventricle.
The usual tip-offs for ependymoma (choice B) are pseudorosettes and structures resembling ependymal canals.
The usual tip-offs for glioblastoma multiforme (choice C) are extreme pleomorphism, necrosis, and hemorrhage.
The usual tip-offs for pilocytic astrocytoma (choice E) are bipolar cells, and location in the cerebellum of young children.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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