asmi
Forum Hero
Topics: 1043
Posts: 4,609
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What is the mechanism of action and uses ?
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| krsma
Forum Elite
Topics: 40
Posts: 227
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Retinoic acid is a neural inductor, and modulates gene expression. It is a derivative of vitamin A. Retinoic acid activates a group of transcription factors that modulate the expression of a number of target genes.
Excess vitamin A can impede neural tube closure.
When retinoic acid binds to the receptors the complex acts as a transcription factor to activate specific genes.
These genes affect the development of the brain. Some of these target genes sonic hedgehog and Hox genes. Deficiencies and excess retinoic acid consumption during pregnancy can cause inappropriate expression of retinoic-induced gene expression
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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thanks..
It works like steroid by binding to receptors in nucleus.
What about isotretenoin ? What test will you do before giving it to young women ?
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| robsanchez
Forum Junior
Topics: 13
Posts: 50
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maybe a pregnant test?
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| robsanchez
Forum Junior
Topics: 13
Posts: 50
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ups sorry pregnancy test....
I think you need two negative pregnancy tests, and use contraception
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