keepgoing Forum Fanatic

Topics: 115 Posts: 2,336
| | 04/13/07 - 08:50 AM  
 
|   #1 |
One approach to vaccination against tumors is to infect dendritic cells, isolated from patients, with recombinant viruses that are engineered to express large amounts of short peptides within the lumen of the endoplasmic reticulum that are retained within the endoplasmic reticulum by specific localization signals. The peptides are engineered to correspond in sequence to tumor-associated antigens. These dendritic cells are then reintroduced into the patients as a “vaccine” to induce anti-tumor immune responses. Such a strategy would be employed specifically to... a. induce secretion of peptides to stimulate antibody responses from tumor-specific B cells b. generate large numbers of MHC class II-peptide complexes to stimulate tumor-directed CD4+ T cells c. generate large numbers of MHC class I-peptide complexes to stimulate tumor-directed CD8+ T cells d. generate large numbers of CD1-peptide complexes to stimulate tumor-directed natural killer cells e. generate large numbers of MICA-peptide complexes to stimulate tumor-directed neutrophils and macrophages
___________________ God,be my strength.
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| new_n_lost Forum Hero

Topics: 724 Posts: 6,388
| | 04/13/07 - 11:13 AM  
 
|   #2 |
b. generate large numbers of MHC class II-peptide complexes to stimulate tumor-directed CD4+ T cells
___________________ "never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| jole Forum Elite
Topics: 18 Posts: 350
| | 04/13/07 - 11:49 AM  
 
|   #3 |
c. generate large numbers of MHC class I-peptide complexes to stimulate tumor-directed CD8+ T cells
___________________ Never underestimate the power of prayer.
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| doc179 Forum Guru
Topics: 67 Posts: 1,217
| | 04/13/07 - 03:01 PM  
 
|   #4 |
C
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| usmlefever Forum Senior
Topics: 4 Posts: 127
| | 04/13/07 - 08:11 PM  
 
|   #5 |
c b/c its related to tumor
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| doc179 Forum Guru
Topics: 67 Posts: 1,217
| | 04/16/07 - 11:00 AM  
 
|   #6 |
Keepgoing..whats the answer for this qn ?
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| keepgoing Forum Fanatic

Topics: 115 Posts: 2,336
| | 04/16/07 - 01:33 PM  
 
|   #7 |
sorry for late reply.. yes right answer is C- generate large numbers of MHC class I-peptide complexes to stimulate tumor-directed CD8+ T cells
___________________ God,be my strength.
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| doc179 Forum Guru
Topics: 67 Posts: 1,217
| | 04/16/07 - 01:42 PM  
 
|   #8 |
Thank you Keepgoing 
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