Spivix
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question from smashstep1.com
A 48-year-old woman complains of a mass on the front of her neck. She states that she sometimes has difficulty catching her breath. Her lips feel tingly, and she says that sometimes her muscles twitch for no apparent reason. Examination of the neck reveals a stone-hard thyroid gland. Biopsy of the thyroid would most likely show which of the following?
a. Diffuse lymphocytic infiltration
b. Malignant papillae with ground-glass nuclei and psammoma
bodies.
c. Diffuse fibrosis
d. Granulomatous inflammation
e. Multiple tissue types, including skin, cartilage, and sebaceous
glands
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| new_n_lost
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b. Malignant papillae with ground-glass nuclei and psammoma bodies. Papillary Ca
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| salmonella
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isnt it Reidels thyroiditis..
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| new_n_lost
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damn u r Right Salmonlla it can be Riedel Thyroiditis cos the presentations is almost the same but teh Stony Hard Appearence is characteristic for Riedel's
The Answer shud be C. Diffuse fibrosis
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| me007
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how hypocalcemia fits in Riedel's?
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| new_n_lost
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i dont think the cause of Muscle twitching will be Hypocalcemia i think it wud be the invasion of the cervical plexus cos her lips tingling n twitching r not in different areas SO maybe i m not so sure on this one but th eStony Hard appearence n resemblence with a Ca of thyroid the other possibility is of Reidel's
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| Luckyall
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Reidel's thyroiditis---> thyroid is replaced by fibrous tissue---> clinically MIMIC CARCINOMA
----> extension of fibrous tissue into surrounding tissue ( can even go to trachea to obstruct, can be associated with mediastinal obstruction...)
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| me007
Forum Guru
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Riedel's mimic carcinoma bcs it "stone hard".
my guess it medullary carcinoma, just choices for histo bizarre.
By exclusion a.
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| epica
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For MEN should be " 3 P"...
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| Spivix
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Explanation: Choice (C) is the correct answer. Riedel's thyroiditis is a rare from of thyroiditis that results in dense fibrosis of the thyroid gland that can lead to hypothyroidism. Compression of the trachea or esophagus may result in dyspnea or dysphagia, respectively. Physical exam shows a stone-hard or woody thyroid mass. Riedel's thyroiditis is associated with antithyroid antibodies. Involvement of the parathyroid glands can lead to hypocalcemia.
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| jole
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Thanks Spivix.nice explanation
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