new_n_lost
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An 18-year-old college student presents to the student health center complaining of a sore throat and fever. He describes feeling tired for the past few days and reports a loss of appetite. On examination, he has pharyngitis with cervical lymphadenopathy. Blood tests reveal lymphocytosis and the presence of heterophil antibodies. Which of the following best describes the virus responsible for his illness?
A. Double-stranded, enveloped DNA virus
B. Double-stranded, nonenveloped DNA virus
C. Single-stranded, enveloped RNA virus
D. Single-stranded, nonenveloped DNA virus
E. Single-stranded, nonenveloped RNA virus
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| jazzblue
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A. EBV
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| new_n_lost
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Anyone Else Who wants to give it a try
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| jazzblue
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new-n-lost, what's the answer?
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| new_n_lost
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Buddy U r Right
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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The correct answer is A.
This is one of those USMLE-style items where figuring out the diagnosis is the easy part and remembering the basic science details is much tougher. In this case, the patient has all the hallmarks of mononucleosis (the heterophil antibodies should have confirmed your suspicion from the history and physical). Mononucleosis is caused by the Epstein-Barr virus, which, in turn, belongs to the herpesvirus family. The herpesviruses are enveloped viruses with double-stranded DNA.
Remember that in addition to Epstein-Barr virus, the herpesvirus family also includes herpes simplex (1 and 2), varicella-zoster (chickenpox, shingles), and cytomegalovirus (infection in immunocompromised). Cytomegalovirus also causes infectious mononucleosis, but in these patients the heterophil test is negative.
There are two families of viruses that are nonenveloped with double-stranded DNA (choice B): papovaviruses and adenoviruses.
There are many families of viruses that are enveloped with single-stranded RNA (choice C): arenaviruses, bunyaviruses, coronaviruses, filoviruses, flaviviruses, paramyxoviruses, orthomyxoviruses, retroviruses, rhabdoviruses, and togaviruses.
Parvoviruses are the only family of DNA virus with single-stranded DNA. They do not have an envelope (choice D).
There are two families of RNA virus that are single-stranded without an envelope (choice E): caliciviruses and picornaviruses.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| jazzblue
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whew, thought i was wrong
nice explanation
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| new_n_lost
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| lq2006
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A. Double-stranded, enveloped DNA virus
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| SmokyWaters
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a
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| SmokyWaters
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| drduck
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A
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| GoodGirl
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A.
But I could only remember it bc I'm doing this topic right now, God only know how it will be in one month. 
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