new_n_lost
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A 34-year-old HIV-positive man without previous opportunistic infections presents complaining of dyspnea with daily activity. He states that he has had a mild cough and fever but denies having had chills, sputum production, or chest discomfort. Physical examination is remarkable for oral thrush and a few small, nontender cervical lymph nodes. A chest x-ray film reveals bilateral interstitial
infiltrates, and bronchoalveolar lavage reveals small silver-staining cysts.
In which other patient population in the U.S. is this organism a frequent cause of a life-threatening pneumonia?
A. Bone marrow transplant patients
B. Hospitalized adults on antibiotic therapy
C. Late-term pregnant women
D. Normal adults in periods of stress
E. Premature infants
F. Preschool children
G. Sexually active adolescents
H. Third-trimester fetuses
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| jazzblue
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A
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| new_n_lost
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Anyone else who Wants to give it a try
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| jazzblue
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Is it E?
But I'd still be surprised if it's not PCP that occurs in immunosuppressed populations.
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| jole
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A
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| new_n_lost
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| new_n_lost
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The correct answer is E.
This patient has Pneumocystis carinii pneumonia, the most common atypical pneumonia in AIDS patients. The next most common pool of at-risk individuals consists of premature infants.
Bone marrow transplant patients (choice A) would be immunologically compromised, and might be a second at-risk group (behind premature infants), but would not be the first choice on this list.
Hospitalized adults on antibiotic therapy (choice B) might be slightly immunologically compromised or stressed, but are not the major patient pool at risk for this infection in the U.S.
Late-term pregnant women (choice C) are not immunologically compromised and would not be at risk.
Normal adults in periods of stress (choice D) are not particularly susceptible to opportunistic pathogens.
Preschool children (choice F) have normal rates of exposure to P. carinii, as would any adult, but are not susceptible to serious pneumonia with this agent unless they are immunologically suppressed.
Sexually active adolescents (choice G) would have the same infection rates as normal infants and adults, but again would not be susceptible to life-threatening pneumonia. P. carinii is transmitted via aerosols, not sexual activity.
Third-trimester fetuses (choice H) are not susceptible to infection with this fungus, although they may become infected in utero with HIV.
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| mytime
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Either C or G....probably the latter.
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| jazzblue
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PCP is a pneumonia caused by the fungal organism Pneumocystis carinii, which is widespread in the environment, and is not a pathogen (does not cause illness) in healthy individuals.
However, in individuals with weakened immune systems due to cancer, HIV/AIDS, solid organ and/or bone marrow transplantation, as well as individuals receiving chronic corticosteroids or other medications that affect the immune system, Pneumocystis carinii may lead to a lung infection.
http://www.nlm.nih.gov/medlineplus/ency/article/0...
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| new_n_lost
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The Questions Asks the next Most Common Grp of Pts in US who will have the PCP
Edited by new_n_lost on 04/09/07 - 08:15 PM
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| new_n_lost
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Although Like u i too did pick A BMT pts but i m looking into CDC Database to Find out the List of the Grp of Pts for having the Likelihood of the PCP in US
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mytime
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GUess what NNL ,don't laugh ok?! I saw the oral thrush and all else became a blurrrrrrrrrrrrr! 
First time this happened......hope the last too!
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| new_n_lost
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I think Wht the Question asks is that is the Population in which PCP can be a really big Risk factor n the CDC says that the Children born to HIV positive Mothers r more likely to have the disease n furthermore Children born PRematurely can be infected too.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| jazzblue
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good to know these info, thanks
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| lq2006
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E. Premature infants
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| SmokyWaters
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its premature infants...
the other populatinos having this P. jeroveci....the oppurtunistic fungus include malnourished babies IC adults and kids
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| drduck
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very good Q....
and nice discussion to end....
even i went for the C.....only saw cadidiasis.....
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| GoodGirl
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Nice Qs and better discussion, as always, I again learned a new thing. 
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