new_n_lost
Politically InCorrect
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- A 35-year-old woman with a history of recurrent anaemia was noted to have target cells and Howell-Jolly bodies on a blood film examination.
Investigations revealed:
Haemoglobin 7.0 g/dL (11.3-16.5)
MCV 77 fl (80-96)
MCH 26.2 pg (28-32)
Serum B12 140 ug/L (160-760)
Red cell folate 95 ug/L (160-640)
Serum ferritin 10 ug/L (15-300)
What disease specific antibody is most likely to be present?
1) Anti-endomysial.
2) Anti-gastric parietal cell.
3) Anti-glutamic acid decarboxylase.
4) Anti-intrinsic factor.
5) Antimitochondrial.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mytime
Kick my butt!
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5? Too tired to think straight now........ God knows how many wrong ans i chose.
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| new_n_lost
Politically InCorrect
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 Nobody Answers n So many Views Cmon Guys SHOW UR GUTS
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
Politically InCorrect
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This was the one which was the toughest one Kudos to u Mytimne atleast u tried n didnt give up
1) Anti-endomysial.
The patient has hyposplenism as suggested by the blood film and a mixed anemia. Celiac disease could therefore fit the above picture with anti-endomysial antibodies being the most appropriate selection from the above list. Antimitochonrial antibodies are seen in PBC, anti-gastric and anti intrinsic Abs are seen in pernicious anemia. Anti-GAD abs are found in auto-immune DM.
Screening for celiac disease should include high-risk groups such as anemia (iron or folate deficiency), hyposplenism, reduced bone density and infertility.
"Anti-endomysial IgA antibodies are extremely specific markers for CD and for dermatitis herpetiformis. These antibodies are directed to a component of the gut endomysial (connective tissue surrounding smooth muscle fibers of the gut)."
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mytime
Kick my butt!
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Wouldn't have known this one .........
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| obgyne2b
Forum Junior
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Target cells and Howell-Jolly bodies are seen in megaloblastic anemia, I pick anti-intrinsic factor antibodies, which is a cause of vitamin B12 deficiency and this anemia.
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