A man who has alkaptonuria

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A man who has alkaptonuria

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13 Posts

us_doctor
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04/02/07 - 11:59 PM

A man who has alkaptonuria marries a woman who has herediatary sucrose intolarence.Both are autosomal recessive diseases and both map to 3q with a distance of 10cM separating the two loci.What is the chance they will have a child with alkaptonuria and sucrose intolerance ?

1. 0%
2. 12.5%
3. 25%
4. 50%
5 100%

pls give you ans with explanation if possible.

new_n_lost
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04/03/07 - 03:48 AM

cant say where is this question from ??

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doc179
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04/03/07 - 04:42 AM

isn't it 0%,as the father has alkaptonuria and mother has sucrose intolerance. The child will be heterozygous for both of the diseases and phenotypically normal

us_doctor
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04/04/07 - 02:37 AM

yes doc179,
u r right nod

@new_n_lost
from kaplan genetics

freshdoc

04/05/07 - 06:00 PM

I would say ZERO.( O% ).

doc179
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04/05/07 - 07:19 PM

Thanx us_doctor wink

Medusin
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04/22/07 - 01:19 PM

I understand the concept... but you say both alterations are in chromosome 3q 10cM apart?

What is the 10 cM?

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mytime
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04/22/07 - 01:30 PM

CentiMorgans just a unit used for mesuring the distance between the genes/alleles.

Medusin
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04/22/07 - 06:43 PM

oh ok. thanks!

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lq2006
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05/25/07 - 05:23 PM

#10

dncosta
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05/25/07 - 05:44 PM

#11

Jackofknives
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05/26/07 - 01:18 PM

#12

Why is 10cM and locus position given? we are not doing gene testing here. Does MLE often give irrelavent info?

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doc179
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05/28/07 - 02:00 AM

#13

well I guess thats how they make us scratch our head, get confused about a simple qn.

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