dxtxpx Forum Guru
Topics: 259 Posts: 1,233
| | 02/24/04 - 08:05 AM  
 
   
 
|   #1 |
L-type Ca+2 channels of sarcolemma : a) Large sustained conductance, inactivate fast b) minimal in cardiovascular system, are responsible for plateau phase of action potential c) may trigger release of internal Ca+2 d) resistance to Ca+2-channel blockers e) cardiac L-channels are regulated by ATPase
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| asmi Forum Hero
Topics: 1043 Posts: 4,609
| | 02/24/04 - 10:40 AM  
 
   
 
|   #2 |
c...?
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| dxtxpx Forum Guru
Topics: 259 Posts: 1,233
| | 02/24/04 - 10:42 AM  
 
   
 
|   #3 |
correct L-type channels: Large sustained conductance, inactivate slowly, widespread in cardiovascular system, are responsible for plateau phase (slow inward current) of action potential, may trigger release of internal Ca++, sensitive to Ca++-channel blockers, cardiac L-channels are regulated by cAMP-dependent protein kinase (phosphorylation enhances probability of channel opening at a given membrane potential)
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