asmi
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A 35-year-old woman consults a dermatologist because of a persistent facial rash. Physical examination demonstrates an erythematous rash,
without blistering or ulceration, involving both cheeks and the nose. The nasolabial folds are relatively spared. The dermatologist also notes
scattered erythematous, firm, maculopapular lesions elsewhere on the woman's face and on exposed areas of the neck, upper chest, and
elbows. Careful examination of the scalp demonstrates a few areas of focal alopecia. On questioning, the woman reports that she has had the
rash more or less continuously for about six months, and that it gets much worse when she is exposed to sunlight.
1.Which of the following autoimmune diseases would most likely produce this patient's skin problems?
/ A. Dermatomyositis
/ B. Progressive systemic sclerosis
/ C. Rheumatoid arthritis
/ D. Sjögren syndrome
/ E. Systemic lupus erythematosus
2.The dermatologist biopsies the rash and sends the sample for pathologic examination. The biopsy shows liquefactive degeneration of the
basal layer of the epidermis accompanied by edema at the dermal junction. Immunofluorescence microscopy would most likely demonstrate
which of the following?
/ A. Granular deposition of immunoglobulin and complement along the dermoepidermal junction
/ B. Granular deposits of lgA selectively localized to the tips of dermal papillae
/ C. Lacy network of lgG deposits in the intercellular spaces lining the keratinocytes
/ D. Linear basement membrane depositions of immunoglobulin and complement
/ E. No deposits of immunoglobulin or complement
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| dxtxpx
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E & A :?:
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| asmi
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Topics: 1043
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yes u r correct dxtxpx 
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