new_n_lost
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SORRY GUYS i WILL POST THE ANSWERS TO ALL MY QUESTION LITERALLY DEAD TIRED NEED TO SLEEP I HOPE U DONT MIND
Rapid IV injection of amiodarone could cause hypotension, which of the following mechanisms is most probable?
a) negative inotropic effect.
b) alfa-2 receptor agonist activity.
c) muscarine receptor agonist activity.
d) through it´s excipient polysorbate.
e) NT depletion.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mms
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amiodarone has a broad spectrum of action blocking Na, Ca and K channels. It also blocks beta adrenoreceptors so it can have a negative inotropic effect
Is it A) ?
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| me007
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d.
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| new_n_lost
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BAng On Target Me007
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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Intravenous amiodarone has many different hemodynamic effects, largely because of its multiple pharmacologic actions.
First, as a result of its direct effect on smooth muscle and its ability to block calcium channels and {alpha}-adrenergic receptors, intravenous amiodarone dilates coronary arteries and increases coronary blood flow.
It also causes peripheral arterial vasodilation and reduces afterload and systemic blood pressure. The reduced blood pressure seen with the intravenous form of amiodarone has complicated the use of this form, particularly in the setting of a rapid infusion.
In a dose-ranging study of intravenous amiodarone hypotension occurred in 26% of patients, but no dose-response relation was found. Some authors have suggested that part of the drug-induced hypotension may be secondary to the effects of amiodarone's vehicle, polysorbate 80
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mms
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| new_n_lost
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i had the same feeling when i did the question MMS literally more than u can imagine n i was so infuriated that i had to rechk the answer.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| sherry39
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aaaaaaa
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