new_n_lost
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A 25-year-old woman develops extensive pruritic wheals following ingestion of seafood to which she was allergic. While these lesions are usually not biopsied, a biopsy would probably show which of the following features?
A. Dilated superficial lymphatic channels
B. Granular complement and IgG at dermal/epidermal junction
C. Microscopic blisters
D. Munro microabscesses
E. Solar elastosis
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| mytime
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i need to revise but wil go with B.
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| jole
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D?
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| new_n_lost
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| chemamr
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very easy one?
I'm guessing completely. A?
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| new_n_lost
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lol Good Guess Amigo
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| new_n_lost
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The correct answer is A. Urticaria (hives) are pruritic wheals that form after mast cells degranulate and trigger localized dermal edema with dilated superficial lymphatic channels. The mast cell degranulation is sometimes, but not always, triggered by IgE-antigen interactions.
Granular complement and IgG deposition at the dermal/epidermal junction (choice B) is a characteristic of systemic lupus erythematosus.
Microscopic blisters (choice C) are a characteristic of dermatitis herpetiformis.
Munro abscesses (choice D) are a characteristic of psoriasis.
Solar elastosis (choice E) is found in actinic keratoses.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| chemamr
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good 
Edited by chemamr on 03/27/07 - 05:20 PM
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| me007
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igG depositions - SLE,
igA - dermatitis herpetiformis in gluten entheropathy
is there something else specific?
(i mean ig deposits in skin)
Edited by me007 on 03/27/07 - 05:19 PM
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| new_n_lost
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In Relation SLE or ???
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| mytime
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HEY THIS ONE IS GOOD 
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| new_n_lost
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In Relation to Skin
Pemhigus Vulgaris = IgG antibodies against Desmosomes
Bullous Pemphigoid = IgG antiboides again Basement Membrane
this is all i cud think of Plz Extend the info if u have more or found more
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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