new_n_lost
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An 18 year old student is admitted with severe crushing central chest pain with associated nausea and profuse sweating. He admits to smoking cocaine. What is the mechanism of myocardial ischemia?
A. Coronary thrombosis
B. Tachycardia
C. Alpha receptor blockade
D. Coronary vasospasm
E. Parasympathetic activity
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| tanmaynator
Forum Senior
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b tachycardia..
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| keepgoing
Forum Guru
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not sure seems both rt tachycardia and c.vasospasm
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| rock
Forum Elite
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contary to the title of the question, this one does not seem easy to me ...well i know cocaine can cause c. vasospasm, it can also cause tachycardia because of it sympathomimetic actions which can cause MI in a susceptible individual because of increased O2 demand...and it can also cause thrombosis.
well my guess is on c. vasospasm in such a young individual.
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| new_n_lost
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 Right On Rock n KG
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
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In acute cocaine exposure, the vasoconstrictive action of the drug seems to be the predominant effect. Both coronary vasoconstriction resulting in myocardial ischemia or infarction and systemic vasoconstriction resulting in hypertension or organ ischemia (particularly cerebral) are observed. Cocaine is known to block the reuptake of norepinephrine and dopamine at preganglionic sympathetic nerve endings, and this action of cocaine is presumed responsible for the increase in heart rate and blood pressure and the acute vasospastic syndromes observed in individuals who use cocaine. Pathologic similarities between cocaine cardiomyopathy and those seen in pheochromocytomas suggest that chronic adrenergic stimulation may play a role in the development of cocaine cardiomyopathy.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| mms
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probably D
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