new_n_lost
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Rheumatoid factor may be present in each of these conditions, except
A) Adult Still's disease
B) Subacute bacterial endocarditis
C) Vasculitis syndromes
D) Sarcoidosis
E) Sjögren's syndrome
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| shalini.ravi
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b 
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mediocricity aint my style
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| usmle4me
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B
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| keepgoing
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B
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| new_n_lost
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Answer: A
Explanation: Patients with adult Still's disease are "seronegative" and lack serum rheumatoid factor. Rheumatoid factors are antibodies specific for the region of the Fc portion of human IgG. Although present in 75 to 80% of rheumatoid arthritis patients, primarily those with HLA-DR4 haplotype, they are by no means specific for this disorder and are found in normal individuals as well as patients with a variety of other inflammatory illnesses.
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| new_n_lost
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This may Suprise u but the SBE pts
Rheumatoid factor: A positive rheumatoid factor is observed in 40-50% of patients with endocarditis of more than 6 weeks' duration. Immune complexes are also observed in patients with prolonged disease.
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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