new_n_lost
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A 32-year-old Turkish man presents with painful mouth sores, a painful red eye and polyarthralgia. Ulcers on a yellow base with erythematous edges are seen in the buccal mucosa. What is the most likely diagnosis?
A Crohn’s disease
B Behçet’s syndrome
C Syphilis
D Reiter’s syndrome
E Erythema multiforme
Explain Ur Answers PLZ
Edited by new_n_lost on 03/21/07 - 04:30 PM
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| girl^interrupted
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B... autoimmune...
Ulcers on a yellow base with erythematous edges are seen in the buccal mucosa.....are aphthous ulcers , thats y can b confused with crohn's.
Polyarthralgia and uveitis can b confused with Reiter's ....
But these 3 combined are typical of Behcet's syndrome...
Thats all I knw
Edited by girl^interrupted on 03/22/07 - 06:51 AM
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| rock
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b-bechets...he has arthralgia+mouth ulcers+uveitis.
just sharing something i knew...the symptoms for bechet's depend on the area affected and if the arteries are involved then it could cause arteritis which could cause deadly complications like stroke or pulmonary embolism.
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| new_n_lost
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Behçet’s syndrome is characterized by recurrent orogenital ulceration, uveitis and arthritis and is more common in Turkish and Chinese populations. It is an autoimmune disease associated with HLA-B12 and -B5. Erythema nodosum, pathergy (abnormal response to tissue injury, e.g. skin ulceration and sepsis following trauma or venopuncture), abdominal pain and diarrhea, headache, confusion, aseptic meningitis, coma, cranial nerve palsies, seizures and papilloedema are other features of this disease. Blood tests are unhelpful as there is no acute-phase response and autoantibodies are negative, i.e. there are no specific diagnostic tests. Treatment includes colchicine and steroids.
The differential diagnosis includes:
1. Reiter’s syndrome (triad of urethritis, conjunctivitis and arthritis);
2. Crohn’s disease (aphthous ulceration is a feature but is less likely in this case in view of a lack of gastrointestinal symptoms or relevant medical history);
3. Erythema multiforme/Stevens��"Johnson syndrome (but no blistering or target lesions infection or drug-induced precipitating factors are mentioned);
4. Herpes simplex and syphilis infections (but no relevant sexual history in this case).
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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