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Kaplan Qbank USMLE



Author13 Posts
  #1

An Rh-negative women married to a heterozygous Rh-positive man has three children.The probability tha all three of their children are Rh positive is-

A.1:2
B.1:4
C.1:8
D.1:0

  #2

A.1:2

If a Rh-negative woman conceives a child with a Rh-positive partner, the potential exists for the child to inherit its father's Rh-positive blood type. There are two types of Rh-positive men. In 55% of individuals, the man is heterozygous. In this situation, his genetics allow him to produce Rh-negative offspring 50% of the time and Rh-positive offspring the remaining 50% of the time. In the second type of a Rh-positive individual, only Rh-positive offspring can result, a condition known as the homozygous state.

http://www.med.unc.edu/obgyn/direct/rh.htm


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #3

Rh blood type of the father (55% of Rh-positive men are genetically heterozygous for the Rh antigen and, therefore, produce Rh-negative offspring when mating with Rh-negative women 50% of the time.)

http://www.emedicine.com/emerg/topic507.htm


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #4

he is a heterozigous Rh+
Wouldn't it decrease that 1:2?

  #5

Well i maybe wrong but thats all i cud think of

Anyone Else plz Elaborate !!!!!


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #6

looks like 50/50, you are right
similar to AR triat.
50% offsprings will have that allele.
1:2

  #7

Guys.. i think the answer is C 1:8

The Q very clearly asks.. "probability that ALL THREE of their children are Rh positive is-"

The probability of each child being Rh+ is 1:2
But if we take all 3 prob together, we have to multiply the probabilities..

So, 1/2 * 1/2 * 1/2 = 1/8

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"Whether you think you can or whether you think you can't, you're right!" ~ Henry Ford

  #8

BTW, this is a genetics q, not immuno wink


___________________
"Whether you think you can or whether you think you can't, you're right!" ~ Henry Ford

  #9

agree with indidoc...its c...that is 1:8. this is a probability question

  #10

Agree with Indi

___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #11

in genetics probability is equal for each offspring ..it is a heterozygous male and would have 1: 2 probability that offspring will be affected
ans is 1:2


please post the right ans????

  #12

Probability for RH- is ½. Shouldnt be misunderstood as, if you conceive a child that is RH-, does NOT mean the next one will be 100% RH+, that is false logic. I think this is what you meant.

Therefore, the chance for each single child to become RH- is ½.

Child #2 is also ½.

Child #3 is also ½.

I forgot the math term for this kind of calculation. But it's ½^3 = 1/8

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There are many things in this world that can’t be changed no matter how hard you try. That’s why you must not hesitate when the time comes where you have to give it all you’ve got.

  #13

probability FOR ALL THREE of their children are Rh positive is 0.125 (1:8)







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