anne
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can any one explain me why there's hypercalcemia in sarcoidosis?
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| dxtxpx
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http://www.sarcinfo.com/calcium.htm
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| mjl1717
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1) I know most of our books say hypercalcemia but the 14th ed.(pg.1926) of Harrisons says hypercalcemia is rare.
2)No one blood test will diagnose it
3)ACE is elevated in 2/3s of pts
4)hilar adenopath is the mainstay of dx
5)looking at pg2222**Granulomas and alveolar macrophages synthesize --1,25(OH)2-D2 which is responsible for the hypercalcemia
6)So answer to your q is elevated levels of vitamin D.
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| anne
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thanx both of u for explanations.
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| drmka
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in the granulomas producing the D vit is increased...
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