ehseen alam
Forum Newbie
Topics: 1
Posts: 3
|
where are the receptors for steroids located
a osteoclast
b osteoblast
c both
|
| sany
Forum Senior
Topics: 7
Posts: 120
|
Osteclast.
I have come across a situation which gives a hypoestrogen state and asks your question.The role of RANK ligand on osteoclsts is srongly emphasized in bone resorption.You can get a detail explanation in High yield Histology which has some ambiguity .But given the situation I go only for Osteoclast..because you clearly stated Steroid.The same thing holds true for 1,25-(OH)2 vitamin D which acts on Osteoblasts to secrete IL-1 which again acts on Osteoclasts and Calcitonin which act on Osteoclasts and cause bone resorption.I think this is a good start for subsequent discussion and can come up with a conclusion.
___________________
sany
|
| ehseen alam
Forum Newbie
Topics: 1
Posts: 3
|
hi sany......high yield says that the steroid hormones include the vitamin d which clearly acts on osteoblasts....but they havent mentioned specifically about the exogenous steroids (taken for adrenal insufficiency)receptors.....also i want to correct you that osteoBLAST have RANKL NOT RANK WHICH IS ON MACROPHAGES.......it is only when the RANKL AND RANK interact the macrophages become osteoclast...interesting hmmm......
|
| sany
Forum Senior
Topics: 7
Posts: 120
|
Thank you..I am waiting to learn more.
___________________
sany
|
|
| |
| | | | |
