me007
Forum Guru
Topics: 72
Posts: 799
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GFAP
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| epica
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Yes, I know this, but explain pleasee what does it mean and how it works.
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| new_n_lost
Forum Hero
Topics: 663
Posts: 6,107
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1. http://www.acnp.org/g4/GN401000079/Ch079.html
2. http://www.antibodybeyond.com/reviews/antigen-g/g...
Function
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expression of glial fibrillary acidic protein (GFAP) by perivascular cells of many mammalian organs suggests an as yet unknown function of this intermediate filament protein in the maintenance of homeostasis and vascular permeability at the blood-tissue interface.
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GFAP might contribute to form macro-complexes to initiate mitogenic and differentiating signaling for efficient nerve regeneration.
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Serum GFAP is a potential marker for prognosis and outcome in patients with central nervous system disorders.
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useful to diagnose those glial tumours which are difficult to be identified by heamatoxylin-eosin stain or due to rare or unusual site.
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Both measurement of GFAP and S100B is a useful non-invasive means of identifying brain damage with some differences based on the pattern of TBI and accompanying multiple trauma and/or shock.
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GFAP expression is essential for normal white matter architecture and blood-brain barrier integrity, and its absence leads to late-onset CNS dysmyelination.
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GFAP can be used as a specific marker for ethanol-induced alterations of astrocytes.
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Muller-cell GFAP expression may be used as an index to follow possible processes leading to an ischemic insult.
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phosphorylation of GFAP plays a role in non-dividing astrocytes in vivo.
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| epica
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Oh, thank u very much for this search.
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