sweetybokhari
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A 65-year old woman with breast carcinoma was treated with a partial mastectomy.which one of the following suggests a better prognosis?
1) recurrence free in the first 6 months
2)the primary tumor was 2 cm in diameter
3) absence of metastasis in the liver
4)presence of estrogen receptors
5) positivity of only 5 lymph nodes
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| robin082006
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2)the primary tumor was 2 cm in diameter
coufused about 4, is is also a good pronosis
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| dr in trouble
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I think it shud b 4 as the tumors estrogen and progestrone positivity is good prognostic sign.
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| vradojc1
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3) no distant mets!!!
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| Justice
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I think it is (4) - you place then a Pt on tamoxifen to control the disease recurrence
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| amkhit
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Prognostic factors in decreasing chronology are 2,4,5,3,1....So the best answer is 2
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| vradojc1
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people, the most important prognostic factor is stage of the disease! Meaning that Stage IV (4) disease (presence of distant mets) has the worst prognosis. If there are no mets, only then other named factors can make a difference. Otherwise (stage IV), prognosis is abominable.
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| sixfeet
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er +.. pr+ tumors.. <2cm in dia.. her2 neu - are good prognostic factors..
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| usmle12
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so what sthe right answer
any one can list prognostic factors correctly n order of preferance..
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| liliaeliz
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pronostic factor first nodes,then size ,estrogen receptor
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| dr_arc
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TNM classification is the single most important factor for prognosis rest too, but later
ans------2
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| cirus
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1) recurrence free in the first 6 months --> doesn mean anything, maybe occult
2)the primary tumor was 2 cm in diameter --> doesn mean it didn metastesize
3) absence of metastasis in the liver ----> not the only site of metast,so still not it
4)presence of estrogen receptors --> the best in the options ,as the use of tamoxifen will help prevent the recurrence
5) positivity of only 5 lymph nodes---> so it already metastesized...
So 4 is the ans
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| dr_arc
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hey guys i was wrong absolutely and completely
the most important factor for prognosis for breast ca is axillary lymph node status.
estrogen receptor status has less prognostic value than the node status, but is an important predictive factor for response to hormonal therapy.
tumor size is not a good prognostic factor because even smal tumors may have nodal mets.
all this is clearly mentioned in the kaplan gyn notes.
i think that settles this question then.
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| MAGY17
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the correct ans is b
when you said lymph node status is the most important faCTOR IN THE PROGNOSIS YUO ARE RIHG, BUT THE QUUETION ASK THE BETTER
PX FACTOR THAT IN ORDER ARE
1=LYMPH NODE STATUS--->BETTER WHEN IS NEGATIVE THE CHOICE IS POSITIVE FOR THAT EXC
2-TUMOR SIZE---->SIGNIFICANT WHEN LYMPH NODE ARE NEGATIVE, IS MY CHOICE IN THIS QUETION
3-RECEPTOR STATUS--->APROXI 25-30% OF BREAT CA OVERXPRESS HER-2 AND AVEREXPRESS OF THE RECEPTOR IS ASSOCIATED WITH POOR PROGNOSIS, exc too
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| MAGY17
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the correct ans is b
when you said lymph node status is the most important faCTOR IN THE PROGNOSIS YUO ARE RIHG, BUT THE QUUETION ASK THE BETTER
PX FACTOR THAT IN ORDER ARE
1=LYMPH NODE STATUS--->BETTER WHEN IS NEGATIVE THE CHOICE IS POSITIVE FOR THAT EXC
2-TUMOR SIZE---->SIGNIFICANT WHEN LYMPH NODE ARE NEGATIVE, IS MY CHOICE IN THIS QUETION
3-RECEPTOR STATUS--->APROXI 25-30% OF BREAT CA OVERXPRESS HER-2 AND AVEREXPRESS OF THE RECEPTOR IS ASSOCIATED WITH POOR PROGNOSIS, exc too
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