Vignette 2

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Immunology Forum

Vignette 2

Login or Register to post messages

Rated:

(0 votes)

Author

7 Posts

new_n_lost
Forum Hero
avatar

Topics: 724
Posts: 6,390

03/11/07 - 12:55 AM

A 12-year-old junior high school boy was taken to the emergency room because of severe abdominal pains, vomiting and localized swelling of the face. He was also having some difficulty breathing. A history of the patient and his family revealed that the boy suffered from recurrent episodes of abdominal pain since he was 4 years old, as did his mother and maternal grandmother. A complete immunological workup revealed markedly reduced levels of C4 and C1INH in the boy's blood.

the most likely diagnosis :-

A) Leukocyte Adhesion Deficiency
B) Systemic Lupus Erythematosus
C) Hereditary Angioneurotic Edema
D) X-Linked Agammaglobulinemia
E) Severe Combined Immunodeficiency
F) X-Linked Hyper IgM Syndrome
G) Paroxysmal Nocturnal Hemoglobinuria
H) DiGeorge Syndrome
I) Wiskott-Aldrich Syndrome
J) Selective IgA Deficiency

___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

doc179
Forum Guru

Topics: 67
Posts: 1,217

03/11/07 - 01:42 AM

C

Edited by doc179 on 03/11/07 - 05:48 AM

indidoc1
Forum Guru
avatar

Topics: 61
Posts: 1,159

03/11/07 - 03:46 AM

G

___________________
"Whether you think you can or you think you can't, you're right!" ~ Henry Ford

keepgoing
Forum Fanatic
avatar

Topics: 115
Posts: 2,356

03/11/07 - 07:08 AM

ccc

___________________
God,be my strength.

keepgoing
Forum Fanatic
avatar

Topics: 115
Posts: 2,356

03/11/07 - 07:08 AM

ccc

why g indi???

___________________
God,be my strength.

indidoc1
Forum Guru
avatar

Topics: 61
Posts: 1,159

03/11/07 - 08:30 AM

keepgoing wrote:

why g indi???

bcoz i goofed it up sticking out tongue

Sorry .. its CCC

___________________
"Whether you think you can or you think you can't, you're right!" ~ Henry Ford

new_n_lost
Forum Hero
avatar

Topics: 724
Posts: 6,390

03/11/07 - 03:59 PM

C The C1INH (C1-esterase inhibitor) regulates the activation of the classical pathway by preventing excessive C4 and C2 activation by C1. Without this inhibitor, the activation of C1, C2 and C4 are uncontrolled resulting in generation of large amounts of vasoactive peptides. These peptides cause increased permeability of the blood vessels, resulting in localized edema of the tissue. This deficiency results in a disease called Hereditary angioedema. The edema can be in subcutaneous tissues, or within the bowel or upper respiratory tract, where it causes abdominal pain or obstruction of the airway.

___________________
"never argue with a fool, they'll bring you down to their level and beat you with experience" FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

Similar forum topics

Vignette 4
Vignette 3
Vignette 1
Vignette 5

Related resources