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Author9 Posts
  #1

A 35 yo F is referred to you after being found to have blood in her urine during an insurance PE 2 days ago. She showed a normal insurance PE with the exception of 1+ blood on a urinalysis dipstick. She denied any current urinary symptoms and a complete review of systems is normal. She admitted to have 20 pack year Hx of tobacco use and near daily use of ibuprofen for aches and pains. She is sexually active, uses barrier contraception and had her last period 12 days ago. Vital signs and PE are within normal limits. Which of the following is the most appropriate first course of action

A. Blood Test, including BUN, Ceatinine and Tumor markers
B. Cystoscopy and upper urinary tract imaging study
C. Microscopic evaluation of urine
D. No further workup, given tobacco and NSAIDS use
E. 24-h urine analysis for protein and creatinin



  #2

C. Microscopic evaluation of urine

  #3

B ) Cystoscopy and UUTIS

hematuria + smoking +NSAIDS -----------------rule out bladder cancer


___________________
The elevator to succes is broke ,you must take the stairs

  #4

I'm not sure if NSAIDs cause bladder cancer. I'm thinking papillary necrosis, but I'm stumped as to what the best answer to assess for papillary necrosis might be?

  #5

I say B

  #6

yes nsaids do cause bladder cancer on long term use so, rule out bladder pathology.ans is B


  #7

According to this: http://cebp.aacrjournals.org/cgi/content/abstract/15/9/1696

...NSAIDs decrease bladder cancer risk, not increase it.



  #8

Please Post the answer !

___________________
The elevator to succes is broke ,you must take the stairs

  #9

C. is the right Ans. dipstick result for hematuria may give false positive, so microscopic urinalysis is warranted










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