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Kaplan Qbank USMLE



Author8 Posts
  #1

Pt. Artificial respiration administered.
Assuming CO2 production remain constant
50% reduction in alveolar ventilation would result in which of the following?

a. 50% reduction in PACO2
b 50% reduction in PAO2
c. no change in PACO2
d. twice the normal level of PACO2
e. twice the normal level of PAO2

please explain

  #2

D alveolar respiration is inversely porportional to PCO2


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #3

what about alveolar PO2?
Why it is not important?

  #4

Alveolar Po2 is dependent on the PCO2 i.e the Alveolar Cncerntration CO2 will decide the amount of O2 coming in the alveoli. If the conc. of PCO2 is increased the capacity of th ealveoli to accumulate the incoming O2 will be decreased its like a box in a train the capacity it can accomadate is 100 n the already 40 molecules of CO2 r present then only the 60 molecules of O2 will come in n get exchanged with CO2 rather than the otherway around therefore we will have the hyperventilation as the dissolved O2 content is decreased. Its the Dissolved amount of O2 which triggers the carotid receptors rather than amount of CO2 in the present in the Blood


___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."

  #5

Agree with NNL

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I can't change the direction of the wind, but I can adjust my sails to always reach my destination.

  #6

Answer is D.

agree with NNL on alveolar PO2.

  #7

using aveolar gas equation.. pAO2=PIO2-PACO2/R
IF PIO2 IS I40.... IN FIRST CASE IF PACO2=40... HALVIN THE ALV VENTILATION WUD CAUSE PACO2 TO BECOME 80.... PAO2 IN THE FIRST CASE WAS 100 AND NOW IT IS 60... SO OBVIOSLY NOT 50% REDUCTION..

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GOD BE MY SHEPHERD!!

  #8

D.

Try to remember:

1) If alveolar ventilation is doubled, then PACO2 is decreased by half; If alveolar ventilation is halved. then PACO2 is doubled.

2) Also if changing PACO2, always changing PO2; but if changing PAO2, it is not necerssarily to change PACO2, it is not the same case, because only alveolar ventilation effects PACO2.

I hope that they are good enough for us to memorize it.








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