dxtxpx
Forum Guru
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Can someone please explain 'potency' in easy and short way. thanks
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| mistral92
Forum Senior
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potency is the amount of drug need or required to elicit a given reponse...
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| shamila
Forum Newbie
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Most drugs bind reversibly to receptors. Receptor affinity for a drug determines its potency,which is the dose or conc. required to produce a desired response.
The maximum response obtained with a drug is an indication of its efficacy.
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| Huntseatchick
Forum Junior
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Let's say we have two drugs that lower heart rate 10 bpm. The more potent drug will take a smaller amount to drop the heart rate than the less potent drug.
The way I've seen potency questions on exams is usually related to efficacy. Let's say we're talking about two other drugs; these are antihypertensives. The more efficacious drug will bring bp from 180/110 to 120/80, and the less efficacious drug will bring the same initial bp down to 140/100.
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Do not worry about your difficulties in mathematics. I can assure you mine are still greater. -- Albert Einstein
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| dxtxpx
Forum Guru
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thanks u all for your explanations 
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| peekay
Forum Guru
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ON EXAM THEY GIVE U EFFICACY VS DOSAGE CONC. CURVES AND EXPECT U TO UNDERSTAND HOW THIS CURVE MOVE UP AND DOWN AND TO LEFT AND RIGHT. ANY PHARM REVIEW BOOK SHOULD HAVE THESE CURVES.
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