Nan
Forum Senior
Topics: 12
Posts: 159
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A young woman with acute myeloblastic leukomia is treated with intensive chemotherapy and achieves remission of her symptoms. Because the prognosis for relapse is relatively high, a bone marrow transplant is undertaken in her first remission. WHich of the following cytokines administered with the bone marrow cells would have the beneficial result of stimulating lymphoid -cell development from the grafted stem cells?
A. IL - 1
B. IL - 2
C. IL - 3
D. IL - 6
E. IL - 7
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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IL-3 is stimulating myeloid line cells
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| us_doctor
Forum Junior
Topics: 5
Posts: 19
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E. IL - 7
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| Nan
Forum Senior
Topics: 12
Posts: 159
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Why is IL 7? remember the "HOT T-Bone StEAk"? I would think it is IL 3
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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IL3 for myeloid line
IL7 for lymphoid line
having myeloblastic condition IL3 seems to be more appropriate
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| freshdoc
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IL-7 = lymphoid
IL-3 = myeloid
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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this is exactly what i say
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| Nan
Forum Senior
Topics: 12
Posts: 159
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Thanks
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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The Qn asks which would promote the lymphoid line. My choice is E- IL7
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| tompat
Forum Elite
Topics: 39
Posts: 345
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remember IL-7 for lymphocytes, as acylostoma said take a look at 7 n L
again IL-3 for myloid , take a look at 3 n m
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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so what do you think is the answer for this qn, tompat?
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| tompat
Forum Elite
Topics: 39
Posts: 345
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hi doc 179,
here the question is how to stimulate LYMPHOID lineage ok
the fact that this is a new bone marrow has nothing to do with previous malignacy of the myloid (or as may in other cases lymphoid)lineage.
all we have to ensure is that lymphoid cells be established properly as q ask us to do.
so my ans is IL-7
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