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Kaplan Qbank USMLE



Author13 Posts
  #1

Which of the following would tend to increase glomerular filtration rate?(One best answer)

A. An increase in glomerular capillary oncotic pressure

B. Vasoconstriction of the afferent arteriole

C. An increase in hydraulic pressure in Bowman's capsule

D. An increase in renal blood flow

Please help me and give an explanation for easily understanding. Thanks!


  #2

A
one of 2 forces is in favor of filtration

  #3

C hydraulic pressure - I'm pretty sure this means hydrostatic pressure. the main factor effecting gfr is hydrostatic pressure, a minor factor would be renal blood flow or plasma flow.

Babydoc, an increase in oncotic pressure would oppose filtration. This occurs in exercising in a warm environment. the loss of fluid would increase the capilary oncotic pressure and thus decrease GFR. If you are still unclear, type gfr in the post search under my sn. I made up a question with a women who has a low gfr and just came from the gym.



  #4

should be C, agree

  #5

i misread, thought about oncotic pressure in capsule, no A is out
but C is not true either - increasing pressure in BC is not promoting filtration, it opposes it (remember ureter obstruction???)
so the only one left is E......

  #6

lol right looks like I misread too, I was sure it said glomerular capillary, but it says bowmans capsule. So the answer is D, increase in renal plasma flow

  #7

D an increase in the renal blood flow.

Choice A , is not correct as increase in capillary oncotic pressure will reduce filteration decrease the GFR.

Choice B , is not correct as vasoconstriction of afferent arteriole will decrease the blood flow and GFR.

Choice C , is not correct as increase in hydraulic (hydrostatic) pressure in the bowman's capsule will oppose filteration and decrease GFR.


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  #8

Answer D is for sure right.
The explanation:
Normal situation: as plasma is filtred in the glomerulus the protein concentration increases along the way, so at the end of capilary network (termianl capilary)there is the highest protein concentration and this decreases net filtration pressure (higher oncotic p).
Higher blood flow: the blood passes through glomerulus faster, plasma has less time to filtrate, thus at the end the relative protein concentration increase in the terminal capilary is smaller (not so high oncotic pressure). And this means higher filtration pressure here. Termianl capilary will have greater filtration pressure, thus total GF will increase!
Hope ths helps!

GL!

  #9

D.




check out this







Attached Files:
showimage.jpg (128 KB, 29 downloads)
attachment
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  #10

this is the explanation if u like.

good luck


Attached Files:
RENAL BLOOD FLOW.doc (36 KB, 17 downloads)

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  #11

thank god its D, i thought I was in the Twilight Zone when i saw the answers people posted.

This is a very simple concept!

  #12

answer id D

The explanations given here are fine......Plus the Kaplan substantiates it


  #13

I go for D with out thinking twice for obvious reasons.

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