mjl1717
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can anyone gives 4 reasons for an elevated MSAFP?
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| doc_clotaire
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1 ) Most common cause : Gestacional Error Age
2 ) Neural tube defect
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| mjl1717
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also gastroschisis, omphalocele,, fetal death and placental abruption, fetal death
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| Dr.Luck
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can yolk sac tumor be included too?
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| DrVirgo
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Causes of an increased MS AFP are:
Dating error (most common cause)--> Proceed with ultrasound.
If MS AFP is still elevated, causes include:
NTD
Ventral wall defect
Placental blood
Renal disease
Sacrococcygeal Teratoma
If no explanation on sonogram, proceed with Amniocentesis..
Causes of increases MS AFP with a normal AF AFP are:
IUGR
Still birth
Pregnancy induced HTN
It is decreased in Down's and Edwards.
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| Dr.Luck
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& what about yolk sac tumour DR.Virgo?
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| DrVirgo
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Yup, AFP is also a tumor marker for Yolk sac tumor (it would be increased) in children and men with this type of tumor, but this is not an Ob issue, as I think these occur later on in life. correct me if I'm wrong.
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