dxtxpx
Forum Guru
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1 ) decreased renal excretion of uric acid
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| asmi
Forum Hero
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yep 1
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| auubar
Forum Senior
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absolutely
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| peekay
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WHAT HAPEEN IN PATIENT WITH INCREASED CELL TURN OVER. THEY HAVE NORMAL RENAL FXN BUT THAY GET ACUTE GOUT AND HOW ABOUT PERSON WHO IS HGRPT DEFICIENT. I WAS DEBATING ABOUT CHOICE B.WOULD'T U SEE INCREASED IN SERUM U.ACID LEVEL RISE BEFORE IT GOES TO JOINTS.
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| auubar
Forum Senior
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hello Peekay,
In gout, the cause due to decreased excretion of uric acid is much more common than increased production. I forget the exact data, sorry about that.
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| dxtxpx
Forum Guru
Topics: 259
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In the majority of patients (almost 90%) with primary gout, hyperuricemia results from relative renal urate underexcretion ("relative urate underexcretors"), while in about 10% of subjects, hyperuricemia is due to endogenous overproduction of uric acid ("urate overproducers")
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| peekay
Forum Guru
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THANK YOU VERY MUCH EVERY ONE. YOUR HELP IS APPRECIATED
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