kiranmayi
Forum Guru
Topics: 237
Posts: 407
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Transgenic mouse with defect in B2 microglobulin gene. What is the immuno defect?
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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CD8+ cells associated= cell mediated immunity
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| meg
Forum Guru
Topics: 62
Posts: 806
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beta-2 microglobulin is a component of the MHC 1 receptor, so there will be a cytotoxic cell defect( viral, fungal infections, malignancies, delayed hypersentivity)....
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| Huntseatchick
Forum Junior
Topics: 11
Posts: 52
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Exactly, Meg: beta2-microblobulin --> MHC I deficiency. Autosomal recessive transmission, typically presents with upper respiratory infections. No evidence of humoral defect.
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Do not worry about your difficulties in mathematics. I can assure you mine are still greater. -- Albert Einstein
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| kiranmayi
Forum Guru
Topics: 237
Posts: 407
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thank u all
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