Ancylostoma
Forum Guru
Topics: 42
Posts: 642
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Sucked into my question trap???? You must now attempt it !!
A 28 yearold patient with a family history of coronary artery disease complains of pain in his hands and a loss of hand strength. His physical examination reveals enlarges orange yellow tonsils, some elarged lymphnodes in the neck and groin, and hepatomegaly. Lab tests indicate and unusually low cholesterol. What best explains the abnormalities in the patient?
A Defective of cholestero transporter ABC-A1
B Defective Apo - A1
C Defective apo b100
D Deficiency of apo-c2
E Deficiency of CETP
As always explain to why you chose your answer.
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| unique1
InGodITrust
Topics: 19
Posts: 1,405
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These tricks wont work any more Ancy !!!!!
I knew it was a trap 
Sorry , have not read Patho yet . Will try it after going through Patho.
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| new_n_lost
Politically InCorrect
Topics: 653
Posts: 6,086
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i thin k i read somewhere abt Tangiers disease ppl having Orange tonsils their HDL was vitually nil n they normal Apo- A1 is normal n something wrong with Cholesterol transporter Choice A
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FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| new_n_lost
Politically InCorrect
Topics: 653
Posts: 6,086
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Where Bro from u r coming up with such tough questions buddy u r scaring me
this one for no reason had stuck to my mind just remmemdered the rare one
But anyways keep us luring into ur trap
___________________
FORUM RULES-- Those who believe in telekinesis, raise my hand. I get enough exercise just by pushing my luck --P4U World.." The pure and simple truth is rarely pure and never simple."
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| me007
Forum Guru
Topics: 72
Posts: 803
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a. Tangier's disease
transporter defective, can not transfer cholesterol to HDL, plasma cholesterol low.
macrophages are the ones having all cholesterol, all lymphoid organs - tonsils, lymph nodes are enlarged, yellow.
Also lack of cholesterol for myelinisation --> neuropathy
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 642
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yellow colored tonsils+ low cholesterol is pathognomic for tangiers, see Me 007 explanation. Goog Job guys
Edited by Ancylostoma on 02/03/07 - 09:14 AM
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| darkhorse
Forum Elite
Topics: 56
Posts: 275
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nice one
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