ellen
Forum Senior
Topics: 17
Posts: 127
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in goljan rapid review 2007 page no 22 inflammation chapter......in C.SEQUENTIAL VASCULAR EVENT...point 3...increase permeability of venules.....a transudate......should be EXUDATE...PLEASE any buddy correct me.in acute inflammation if u listen his audio says exudate...so...any explaination?
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| me007
Forum Guru
Topics: 72
Posts: 799
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you are right
exudate - protien-rich and cell-rich, due to acuute inflammation with increased vasc permeability
produce swelling but no pitting edema
transudate- protein-poor and cell-poor, due to incr in hydrostatic pressure or decr oncotic pressure.
produces pitting edema
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 637
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I agree with everythin me007 says. Their are alot of typos in books thesedays.
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| ellen
Forum Senior
Topics: 17
Posts: 127
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thanks.
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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in inflammation PERMEABILITY increased so there is in fact TRANSSUDATE
and it is absolutely not necessary BACTERIAL inflammation with NEU and PROTEIN rich fluids
the one he referrs to is ANY TYPE of inflammation and as a resul of INCREASED PERMEABILITY due to histamin and other vasoactive peptides plus increased blood flow and increased pressure there will be TRANSUDATE in the interstitium (edema)
hope it helps
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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in any event, at the end exudate or transudate is determined by it's content - protein, cells, etc, not just presence or abcence of inflamation (which can be suppurative, aseptic, fibrinous, etc)
just my 2 cents
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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i think i got it
in any inflammation there are initial processes like vessel consriction-relaxation, increase in flow and permeability leading to TRANSUDATE
if inflammation is not microbial (without Neu involvement) it will stay as transudate, but as soon as Neu are attracted by certain molecules (C5a) and Neu get involved - we have EXUDATE (protein rich fluid) coming out ov vascular region into intertitium (Neu damage by collagenase)
anybody agrees?
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| unique1
InGodITrust
Topics: 20
Posts: 1,450
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babydoc4usmle, I agree. You are absolutely right on what you said on your last ( Feb.9th) post 
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| extrapyramidal
Forum Newbie
Topics: 4
Posts: 28
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agree with babydoc...
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