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lac operon
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Author4 Posts
  #1

An investigator has isolated a bacterium that, in the absence of glucose, constitutively produces the proteins coded for by the lac operon. Which of the following statements explains this observation?

A)the promoter has a mutation that prevents RNA polymerase from binding

B)there is missense mutation in the gene for beta-galactosidase

C)the gene for the catabolite activator protein is mutated and inactive

D)there is a mutation in the attenuator sequence

E)the gene for the repressor protein is mutated and inactive


please explain your answer, thanx

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  #2

E

if no repressor protein --> nothing stopping Lac Operon from expression

  #3

http://www.prep4usmle.com/forum/thread/70314/

somewhat related question, please answer


  #4

E
If proteins are constantly produced in absence of glucose then we can think about 3 possibilities:
1-repressor is absent
2-repressor can't bind to operator
3-operator is defective








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