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Kaplan Qbank USMLE



Author10 Posts
  #1

how do loop diurectics and thiazides cause vasodilation?shaking head Does anybody know the mechanism? Thx.

  #2

do they?

  #3

yes, per kaplan note.

  #4

nothing in Katzung -Trevor

  #5

where in kapl notes ? where exactly is mentioned ???

  #6

only cardiovascular complications due to hypovolemia usually mentioned
???

  #7

I think its at the beginning of the htn section. or the beginning of the diruretic section. Check the first couple of paragraphs. It mentions that besides their normal actions to decrease volume, they have additional actions that cause vasodilation.


  #8

Yeah, correct, it is mentioned in Diuretics chapter in Kaplan..... first paragraph

  #9

so any1 kno the answer??

how do they cause vasodilatation?


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  #10

Furosemide is a venodialator. Effect might be mediated by PGs, requires intact kidney function.







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