Palaniappan
Forum Senior
Topics: 30
Posts: 148
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Hi all..Once again posting with some queries...Drop in your thoughts...
1.In beta thalassemis intermedia-What is the genotype..With beta0/beta1 or something like that?
2.Is there any significant deifference between ostium primum and ostium secundum other than embryologically?
3.In general,Lupus nephritis belongs to which of the main nephritic/nephrotic categories?
4.Vasa recta-a branch of efferent arteriole-supplies medulla..i was wondering ,so,whenever there is cortical necrosis with some occlusion of the renal artery there must be medullary infarct also..Please clarify me.
Thanx
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| me007
Forum Guru
Topics: 72
Posts: 803
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3. SLE - diffuse proliferative glomerulonephritis.
wire looping of capillaries - subendothelial deposits
neutrophilic infiltrations with fibrinoid necrosis
hematoxilin bodies - altered DNA
pathogenesis- DNA-antiDNA IC
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| me007
Forum Guru
Topics: 72
Posts: 803
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4. sort of yes?
http://library.med.utah.edu/WebPath/RENAHTML/RENA...
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 642
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1) Cant remember , just know that some B chains are being produced.
2 Ostium primum is usuall associated with a valvular defect to tricuspic or mitral valve. Downs have ostium primum type. Ostiums secundum most common type of asd overall and no valve defect associated with it.
3 The only lupus you need to know it type 4 diffuse proliferative GN. I had posted a picture with a question on it a while back that babydoc answered
4 The most common locations of injury in ischemic kidney damage is pct, and ascending limb of the loop of henle. They are found in both the Cortex(PCT) and Medulla(ascending limb). Using that you may be able to interpret your answers.
Edited by Ancylostoma on 01/27/07 - 06:25 PM
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| me007
Forum Guru
Topics: 72
Posts: 803
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Thalassemia intermedia. Thalassemia intermedia is a confusing concept. The most important fact to remember is that thalassemia intermedia is a description, and not a pathological or genetic diagnosis. Patients with thalassemia intermedia have significant anemia, but are able to survive without blood transfusions. The factors that go into the diagnosis are:
The degree to which the patient tolerates the anemia.
The threshold of the physician to transfuse patients with thalassemia.
http://sickle.bwh.harvard.edu/thalover.html
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