Clozapine
Forum Elite
Topics: 15
Posts: 167
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A 24 year old man presents to your clinic complaining of painful muscle cramps when walking eight flights of stairs to his new apartment. On further history taking, you learn that he also experiences these severe muscle cramps after lifting weights in the gym. On several occasions, he has had reddish-purple urine after exercising. His blood work showed normal liver enzymes, no rise in serum lactate after strenuous exercise and elevated serum creatine kinase even at rest. Which step of metabolism during glycogenolysis in this man you fear is defective?
a. alpha 1,4:1,4 translocation
b. alpha 1,4:1,6 translocation
c. breakdown of alpha 1,6 linkage in liver
d. breakdown of alpha 1,6 linkage in liver and muscle
e. breakdown of alpha 1,6 linkage in muscle
f. breakdown of alpha 1,4 linkage in muscle
pls explain.
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| residency_2008
Forum Newbie
Topics: 3
Posts: 16
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this is McArdle's disease and the answer is F
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I wOn'T gRaTiFy ThE dEvIl By GeTtInG dIsCoUrAgEd !!
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| Ancylostoma
Forum Guru
Topics: 42
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F, agreed,
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| lnb6des
Forum Newbie
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i also agree with them it's F
glycogen phosphorylase in muscle
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| drplacebo
Forum Senior
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F....Disorder of glycogen breeakdown in muscle...Refer to glycogen metabolism !!
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| MRMAVERICK
Forum Guru
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| freshdoc
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 nice shot
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| drasifmansuri
Forum Newbie
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answer f.. disorder of glycogen metabolism
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| lq2006
Forum Elite
Topics: 43
Posts: 382
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F
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| dncosta
Licensed, finally
Topics: 19
Posts: 604
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F
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