asmi
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Amikacin is ordered for a pt with pyelonephritis due to kleb. pneumoniae.The clearance and volume of distribution of amikacin in this pt are 50 ml/min and 20 L. What dose should be administered every 8 hours to obtain an average steady plasma concentration of 20 mg/L
A.125 mg
B.400 mg
C.480 mg
D.760 mg
E.1000 mg
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| asmi
Forum Hero
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will anybody answer this  :cry:
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| auubar
Forum Senior
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How about D.
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| asmi
Forum Hero
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no...calculate it and show us whats the calculation.
Thanks in advance
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| cprax
Forum Junior
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The answer is "C"
Maintainence dose=Plasma conc. x clearance
=20mg/l x 50ml/l
=20mg/l x .05l/min
=1mg/min
=1mg/min x 60min/h x 8hr
=480mg/min
what is the correct answer?
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| asmi
Forum Hero
Topics: 1043
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yes u r right .
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