babydoc4usmle
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i tend to think A
ADH places H2O-channels and it would decrease Na concentration adn as a respond (to keep concentration in normal range) Na reabsorbtion should go up --> there goes high BP: incr volume and incr Na, but no change in tonicity --> no edema
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| me007
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i'm not alone 
according to Kaplan,A is not correct, because ADH promotes Na excretion, not reabsorption!!!
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| babydoc4usmle
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so what is it?
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| babydoc4usmle
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i remember that in SIADH (which we have here) there is going to be decreased Na concentration with euvolemia and incr urine osmolarity (so Na should be excreted more), but i can't find an answer that would fit better than A....
D is my second and last thought
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| babydoc4usmle
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and giving a second thought...
it could be D, because ADH constantly reabsorbs water, so it has to go out constantly too
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| Ancylostoma
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C The increased pressure and volume causes atrial stretch and leads to increased anp secretion
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| Palaniappan
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SIADH --->Increased water absorption--->Increased ecf volume-->Decreased renin-->decreased alsodterone-->increased sodium excretion--->Natriuresis
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| Luckyall
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Okay this is what i think:
SIADH is a common complic of pulmonary carcinoma. These tumors continuously prod. ADH and ADH prod is not affected by the changes in Osmolaruty serum.
Bon, now ADH--> incr water reabsorbt & decrease Na serum conc. --->increased blood Volume-----> HyperVolemia----> increased BP
HyperVolemia--->streches Atria---> ANP secr.----wich increases Na-uresis & increases diuresis
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| Palaniappan
Forum Senior
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So,I think it can't be A,B OR E.ANP has also a diuretic effect in case of ecf volume...So,I will go with C....
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| Ancylostoma
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lol i'm glad you guys took the time to copy my words 
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| me007
Forum Guru
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my biggest concern is that fact that ADH promotes Na excretion
When BRS physio p 184 -...ADH stimulates Na Cl reabsorption in thick asc limb
correct ans is ANP
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| Luckyall
Forum Guru
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B/c ANP tends to antagonize Renin angiotensin, ADH
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| Palaniappan
Forum Senior
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To add to lucky all...In SIADH,there is normal body volume due to the counteractions of ADH and ANP..
lol..Anky..Now I could sense why youa re spending most of your time in this forum 
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| Ancylostoma
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Listen, Me if you consider the main action on adh as the reabsortion of water by increasing the number of channels in the medullary collecting ducts called aquaporin 2. You will be able to answer all the adh questions. I dont know how Brs physio is but I generally dont like the brs books. Behavioral is allright but besides that I dont like them. I have been always taught what luckyall said. ANP is the antialdosterone. Discard that BRS physio its crap .
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| me007
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i'll ask another way.
why A is not correct?
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| Ancylostoma
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Aldosterone increases renal absorbtion, Adh increases renal excretion of NA. Brs cant be trusted and i have never heard of Adh causing NA reabsorbtion.
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