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Kaplan Qbank USMLE



Author6 Posts
  #1

Could anybody help explain this q? Thanks.

An animal is made diabetic by injection of a drug that destroys
pancreatic b cells. Removal of which of the following organs would
most likely produce a decrease in blood glucose concentration in
this animal?
A. Anterior pituitary
B. Colon
C. Gonads
D. Kidney
E. Pancreas




  #2

E once again I cant be 100% sure, but I'm pretty sure. When we lose insulin we lose on of the regulators og glucagon secretion. This occurs locally, when insulin is normally secreted it inhibits the secretion of glucagon, same or the other way around. The lack of insulin leads to low levels of insulin and glucagon excess that further contributes to the hyperglycemia seen in diabetics. Hope that Helps.

  #3

Thanks An. I chose that as well. But the answer is A. Any idea?

  #4

ant pituitary will release GROWTH HORMONE AND ACTH which wil stimulate release of cortisol both of which are gluconeogenic

  #5

see thats what I was also considering. I knew there was a possibility but I just figured that since the actions of cortisol are long acting, then it would take longer to get the effect. I guess I will rememeber this time for sure. Looks like I had another disgusting memory lapse.



Edited by Ancylostoma on 01/22/07 - 10:54 AM

  #6

Thanks Mr Maverick and An.







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