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Author8 Posts
  #1

A 68-year-old woman has a 3-year history of watery diarrhea and weight loss of 13.5 kg (30 lb). She recently came to the United States from Santo Domingo. Diagnostic studies show bulky, foul-smelling diarrhea and an abnormal D-xylose test.

what is the diagnosis?

what would a small bowel biopsy show?

what's the treatment?

easy one grin


  #2

the diagnosis is celiac sprue, the treatment is avoiding gluten diet, on biopsy there will be villous atrophy with compensatory crypt hyperplasia and lymphocytic infiltration.

  #3

Dx - Tropical Sprue
Biopsy - ???villous atrophy with micro-organisms
Tx - Antibiotics (cotrimoxazole)


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  #4

prathapdoctor wrote:
the diagnosis is celiac sprue, the treatment is avoiding gluten diet, on biopsy there will be villous atrophy with compensatory crypt hyperplasia and lymphocytic infiltration.



Agree with this explanation.

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  #5

more opinions?

  #6

answer given is as cocacola says

-tropical sprue (santo domingo)
-flattened villi plus lymphocytes and plasma cell infiltration
-tetracyclines plus folic acid

celiac and tropical sprue are really very similar, even in the biopsy.

  #7

where is that santodomingo located, the patient just came to usa but the symptoms had been there for the past 3 yrs.the question is a bit tricky.

  #8

yes, a bit tricky. santo domingo is in Republica Dominicana which is close to Puerto Rico.









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