C-11 hydroxylase deficiency hyperkalemia

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C-11 hydroxylase deficiency hyperkalemia

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Lim
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01/20/07 - 05:15 AM

C-11 hydroxylase deficiency has hyperkalemia?

can you tell me why? thanks in advance.

(Kaplan 54p internal medicine 2005ver)

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bozhenka
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01/20/07 - 06:33 AM

Cortisol interacts with the mineralocorticoid receptors as an agonist.

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Guptashutosh
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01/20/07 - 10:54 AM

11-Desoxycortecosterone act as a potent minrelocorticosteriod, whic h is accumulated

Lim
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01/21/07 - 07:46 PM

11-Desoxycortecosterone increase Na+ absorption and decresed Potassium absorption.
so Na+ (up) K+(down)- hypokalemia...is right basically.
but hyperkalemia happens in C-11 hydroxylase deficiency.

I asked about this.

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