chemamr
Forum Hero
Topics: 703
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A patient with a diagnosis of multiple sclerosis goes to your clinic with an acute exacerbation,
1) how do you treat it?
2) if your first choice treatment fails, how do you treat it now?
3) what are the disease-modifying therapies that you could recommend to a pt with this disease? and could they use them throughout pregnancy too?
4) what are suggestive findings for this disease on a cerebrospinal fluid and MRI? what could you expect to find?
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| CocaCola
Forum Guru
Topics: 35
Posts: 907
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1 - Acute attack - steroids
2 - plasmaphoresis
3 - interferons, metotrexate, glatiamer acetate
metotrexate can't be given during preg... not sure about the other two.
4 - CSF - high protein levels (high IgG)... MRI - plaques of demylenation around the ventricles
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| prathapdoctor
Forum Elite
Topics: 12
Posts: 406
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i agree that coco cola, i think mitoxantrone should not be given during pregnancy,only interferons can be given during pregnancy.
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| chemamr
Forum Hero
Topics: 703
Posts: 4,488
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good
Cocacola: I guess you're trying to say mitoxantrone when you say metotrexate, ok.
IFN-beta and glatiramer acetate aren't approved for pregnant or for nursing women.
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