Ancylostoma
Forum Guru
Topics: 42
Posts: 637
|
A 56 year old female begins treatment for severe joint pain and swelling. Several weeks later she presents with cough and hemoptysis. Sputum stain reveals acid fast bacilli, the medication used to alleviate this patients joints symptoms inhibits which of the following processes?
A Purine synthesis
B Pyrimidine synthesis
C Phospholipid degradation
D Prostaglandin synthesis
E TNF alpha
as an add on, can you name the drug, or multiple drugs that have this mechanism of action? Can name the most important side effect(s) ?
answer will be forthcoming after people try it!!!
|
| MRMAVERICK
Forum Guru
Topics: 42
Posts: 756
|
e
|
| MRMAVERICK
Forum Guru
Topics: 42
Posts: 756
|
etanercept and infliximab
|
| Palaniappan
Forum Senior
Topics: 30
Posts: 148
|
It is E...Etanercept can re-activate the latent TB.
|
| Palaniappan
Forum Senior
Topics: 30
Posts: 148
|
Side effect--For sure Infections...Other effects might be due to drug allergy
|
| Ancylostoma
Forum Guru
Topics: 42
Posts: 637
|
both of you guys are right, etanercept, infliximab , adalimumab all block tnf alpha which lead to decrease macrophage function and reactivation of tb. They decrease joint erosion, improve synovitis and slow disease progression and thus are often used in the treatment of Rheumatoid athritis.
|
|
| |
| | | | | | |
