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Kaplan Qbank USMLE



Author10 Posts
  #1

A previously healthy 6-month-old boy is brought to the physician because of a 12-hour history of vomiting and diarrhea. He vomits after all feedings; the vomitus does not contain blood or bile. His mother says that he has had fewer wet diapers than usual during this period. He appears dehydrated and is crying without tears. He is at the 50th percentile for length and 30th percentile for weight. He appears lethargic. His temperature is 38°C (100.4°F), pulse is 180/min, and blood pressure is 60/40 mm Hg. Examination shows sunken eyes, dry mucous membranes, and a sunken anterior fontanel. Arterial blood gas analysis on room air shows:

pH 7.2

PCO2 38 mm Hg

PO2 90 mm Hg

Which of the following is the most likely explanation for this patient's arterial blood gas findings?

A ) Excessive metabolic acid formation

B ) Impaired ventilation

C ) Increased chloride loss

D ) Increased CO2 concentration in the extracellular fluid

E ) Increased metabolic acid produced by the gastrointestinal trac

  #2

D.increased CO 2 conc in the extracellular fluid.

  #3

but now i am thinking of A optioin,my explanation is

fluidloss -> dehydration->hypoperfusion-> increased lactic acid produciton in glycolysis -> lactic acidosis.

  #4

May be it is due to the loss of Chloride from diarrhea , as diarrhea give you metabolic acidosis .

I PICK C


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  #5

A? but not sure.

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  #6

wel i have one explanation here, he has metabolic acidoses due to bicar loss in gi fluid in the form of vomiting and diarrhoea , which he shd have compensated with hyperventilation leadin to compensatory decreace in pCO2 but due to lack of ventilationg pCO2 remains 38 , so he has impaires or say failing respiration i guess ... option B

  #7

A---


impaired ventilation---pCO2 dec-- ruled out
increase chloride loss--in vomiting theres exchange of bicarb wid chloride in the stomach which is thn lost in vomitus.this ll cause metabolic alkalosis-- ruled out
inc co2 conc. --- nt possible since co2 being highly soluble in blood will raise the pco2 also---ruled out
E option ca nt hold there


  #8

C

  #9

I think your explanation makes sense.

prathapdoctor wrote:
but now i am thinking of A optioin,my explanation is

fluidloss -> dehydration->hypoperfusion-> increased lactic acid produciton in glycolysis -> lactic acidosis.



  #10

A, lactic acidosis







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