babydoc4usmle
Forum Guru
Topics: 18
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Thalassemia Fe-deficiet Anemia
Hb decr decr
defective HB insuff Hem synthesis
Hct decr decr
less RBC made
RBC incr decr
unknown same as above
this is as much as i could pull, maybe someone knows more than that?
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| me007
Forum Guru
Topics: 72
Posts: 799
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difference is that there is nothing wrong with Fe in Thal.
Decreased Hb synthesis - alfa - or beta chain of globin.
All Fe studies are normal.
RBC count - normal or increased.
RDW - normal.
Hb phoresis normal in alfa thal.
Alfa and beta minor thal requre no treatment, and treatment of severe forms (severe hemolytic anemia) requre blood transfusions - danger of iron overload
Both - iron def and thal are microcytic.
In iron deficiency serum iron decreased, serum ferritin -(storage form of iron) - decreased, iron binding capacity - increased, saturation - decreased.
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| drsaleh
Forum Newbie
Topics: 5
Posts: 7
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my q was why in thalassemia RBC increase but Hct decrease?
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 631
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the reason for this relationship is UNKNOWN (according to uncle G)
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